Harvoni (ledipasvir/sofosbuvir)
Indicated for the treatment of adults with chronic hepatitis C virus genotype 1,4,5 or 6 infections without cirrhosis or with compensated cirrhosis.Overall cure rate for genotype 1 patients is 97%Duration: Treatment Naïve with viral load < 6 million is 1 pill daily for 8 weeksSide effects: > 10% fatigue, headache
Epclusa (sofosbuvir/velpatasavir)
Indicated for the treatment of adults with chronic hepatitis C virus genotype 1,2,3,4,5 or 6 infections without cirrhosis or with compensated cirrhosis.Overall cure rate for across all genotypes is 98%99% overall cure rate for genotype 295% overall cure rate for genotype 3Duration: 1 pill daily for 12 weeksSide effects: > 10% fatigue, headache
Mavyret (glecaprevir/pibrentasvir)
Indicated for the treatment of adults with chronic hepatitis C virus genotype 1,2,3,4,5 or 6 infections without cirrhosis or with compensated cirrhosis.Overall cure rate for across all genotypes is 98% .Duration: Treatment Naïve without cirrhosis is 3 pills once a day with food for 8 weeksOverall cure rate for genotype 1 is 94-97%
Zepetier (elbasvir/grazoprevir)
Indicated for the treatment of adults with chronic hepatitis C virus genotype 1 or 4 infections without cirrhosis or with compensated cirrhosis.Overall cure rate for genotype 1 is 94-97%Overall cure rate for genotype 4 is 97-100%Duration: 1 pill once daily for 12-16 weeks; May need additional medicine- ribavirinSide effects: > 10% fatigue, headache
Vosevi (sofosbuvir/velpatasvir/voxilaprevir)
Indicated for the treatment of adult patients with HCV infection without cirrhosis or with compensated cirrhosis (Child Pugh A) who have:•GT 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing NS5A inhibitor•GT 1a or 3 infection and have previously been treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor96% Overall cure rate all genotypesDuration: 1 pill daily for 12 weeksSide effects: > 10% fatigue, headache